Fraternal Birth Order Effect

Richard Stanley

Well-Known Member
The following excerpted article discusses a new antibody hypothesis as to the cause of so-called Fraternal Birth Order Effect in relation to male homosexuality tendencies. Some years ago it was suggested that one factor, at least, was that it was discovered that a mother has less and less male testosterone as she ages. (All humans have both sex hormones, just in differing ratios). Maybe both antibodies and hormones play a role?

Prior to a rather early development stage, all pre-differentiated fetuses are sexually ambiguous excepting their X and Y chromosomes, that is. The specific genes involved do not directly determine a sexual outcome, but rather the exact 'correct' or 'incorrect' expression of the respective genes. Individual genes are also known to be effected by epigenes, which can have their functions altered by such as various environmental factors.

Or, maybe the youngest brothers are more feminized by the dominating treatment of their older brothers (and sisters)? Studies have shown that one can change their alpha status hormones by simply changing physical postures and other behavioral attitudes. Such as beta wolves change their status hormones and behavior upon ascending to the alpha pair.

Hmmm, maybe mothers should stop making so many boys? It would be so much better for us males, especially for the oppressed alt-right ones.

The more older brothers a boy has, the more likely he is to be gay when he grows up – an effect called the “fraternal birth order effect”. Now it seems that increasing levels of antibodies in a mother’s immune system could play a role.

Anthony Bogaert at Brock University, Canada, and his team think that some women who are pregnant with boys develop antibodies that target a protein made by the Y chromosome. Our immune systems make antibodies to recognise foreign molecules, which have the potential to be from dangerous bacteria. But pregnant women sometimes also produce antibodies against fetal molecules – for example, if their fetus has a different blood group. Bogaert’s team wondered if maternal antibodies might play a role in shaping sexual orientation.

The team collected blood from 142 women, and screened it for antibodies to a particular brain protein that is only made in males. They thought this would be a good candidate, because it plays an important role in how neurons communicate with each other, and because it is produced on the surface of brain cells, making it relatively easy for antibodies to find and detect it.

They found that the mothers of gay sons with older brothers had the highest levels of antibodies against this protein, followed by the mothers of gay sons with no older brothers. Women who had straight sons had less of these antibodies, while women with no sons had the least.

The team suggests these antibodies build up in some women’s bodies with every male baby they have. At higher concentrations, it is possible that the effect of these antibodies on the protein they target leads to changes in brain development that can have an influence on sexual orientation. ...